{"id":7422,"date":"2026-02-22T00:40:29","date_gmt":"2026-02-21T22:40:29","guid":{"rendered":"https:\/\/www.schooler.org.ua\/uk-uakishkova-flora-ta-zapori-nove-rozuminnja-zdorovja-travlennja-ru\/"},"modified":"2026-02-22T00:40:29","modified_gmt":"2026-02-21T22:40:29","slug":"uk-uakishkova-flora-ta-zapori-nove-rozuminnja-zdorovja-travlennja-ru","status":"publish","type":"post","link":"https:\/\/www.schooler.org.ua\/cs\/uk-uakishkova-flora-ta-zapori-nove-rozuminnja-zdorovja-travlennja-ru\/","title":{"rendered":"St\u0159evn\u00ed fl\u00f3ra a z\u00e1cpa: Nov\u00e9 pohledy na zdrav\u00ed tr\u00e1ven\u00ed"},"content":{"rendered":"

V\u00fdzkumn\u00edci identifikovali dva typy bakteri\u00ed, kter\u00e9 mohou hr\u00e1t kl\u00ed\u010dovou roli p\u0159i chronick\u00e9 z\u00e1cp\u011b<\/strong>, a potenci\u00e1ln\u011b tak otev\u00edraj\u00ed cestu k c\u00edlen\u011bj\u0161\u00ed l\u00e9\u010db\u011b. Studie publikovan\u00e1 v \u010dasopise Gut Microbes<\/em> ukazuje, jak tyto bakterie naru\u0161uj\u00ed p\u0159irozenou lubrikaci tlust\u00e9ho st\u0159eva, co\u017e vede k pomal\u00e9mu tr\u00e1ven\u00ed. <\/p>\n

\u00daloha st\u0159evn\u00ed fl\u00f3ry p\u0159i defekaci<\/h3>\n

Zdrav\u00e9 tr\u00e1ven\u00ed z\u00e1vis\u00ed na vyv\u00e1\u017een\u00e9 st\u0159evn\u00ed mikrobiot\u011b.<\/strong> Bakterie pom\u00e1haj\u00ed rozkl\u00e1dat potravu, vst\u0159eb\u00e1vat \u017eiviny a zaji\u0161\u0165uj\u00ed hladk\u00fd pr\u016fchod odpad\u016f st\u0159evy. Ur\u010dit\u00e9 kombinace bakteri\u00ed v\u0161ak mohou tuto k\u0159ehkou rovnov\u00e1hu naru\u0161it. Studie se zam\u011b\u0159ila na Bacteroides thetaiotaomicron<\/em> a Akkermansia muciniphila<\/em>, kter\u00e9 spole\u010dn\u011b ni\u010d\u00ed mucin, ochrannou, lubrika\u010dn\u00ed vrstvu uvnit\u0159 tlust\u00e9ho st\u0159eva. <\/p>\n

\n

“Tato studie identifikuje specifick\u00fd mechanismus, kter\u00fdm mohou st\u0159evn\u00ed bakterie zp\u016fsobit z\u00e1cpu. Sou\u010dasn\u00e9 l\u00e9\u010dby jsou \u010dasto ne\u00fa\u010dinn\u00e9, proto\u017ee ne\u0159e\u0161\u00ed z\u00e1kladn\u00ed p\u0159\u00ed\u010dinu,” vysv\u011btluje Dr. Tomonari Hamaguchi, hlavn\u00ed autor z Nagoya University.<\/p>\n<\/blockquote>\n

Jak studie odhalila vztah<\/h3>\n

V\u00fdzkumn\u00edci geneticky modifikovan\u00ed B. thetaiotaomicron<\/em>, aby zabr\u00e1nil ni\u010den\u00ed mucinu. Pot\u00e9 transplantovali jak tuto modifikovanou bakterii, tak A. muciniphila<\/em> na my\u0161i. V\u00fdsledky byly ohromuj\u00edc\u00ed<\/strong> : My\u0161i s upraven\u00fdmi bakteriemi si zachovaly neporu\u0161en\u00fd mucin tlust\u00e9ho st\u0159eva a m\u011bly pravideln\u00e9 pohyby st\u0159ev. To potvrzuje, \u017ee kombinace t\u011bchto dvou bakteri\u00ed je rozhoduj\u00edc\u00ed pro naru\u0161en\u00ed zdrav\u00e9ho tr\u00e1ven\u00ed. <\/p>\n

Pro\u010d je to d\u016fle\u017eit\u00e9?<\/h3>\n

Z\u00e1cpa je extr\u00e9mn\u011b \u010dast\u00fdm probl\u00e9mem, jeho\u017e v\u00fdsledkem je 2,5 milionu n\u00e1v\u0161t\u011bv l\u00e9ka\u0159e ro\u010dn\u011b jen v USA<\/strong>. Chronick\u00e1 z\u00e1cpa postihuje a\u017e 20 % severoamerick\u00e9 populace, p\u0159i\u010dem\u017e vy\u0161\u0161\u00ed v\u00fdskyt je pozorov\u00e1n u \u017een a star\u0161\u00edch dosp\u011bl\u00fdch. Sou\u010dasn\u00e1 l\u00e9\u010dba je \u010dasto do\u010dasn\u00e1, proto\u017ee ne\u0159e\u0161\u00ed z\u00e1kladn\u00ed p\u0159\u00ed\u010dinu. <\/p>\n

Tento nov\u00fd v\u00fdzkum nazna\u010duje, \u017ee zm\u011bna rovnov\u00e1hy t\u011bchto bakteri\u00ed by mohla v\u00e9st k \u00fa\u010dinn\u011bj\u0161\u00edm a dlouhodob\u00fdm \u0159e\u0161en\u00edm. Nen\u00ed jasn\u00e9, jak moc jsou tyto bakterie v populaci roz\u0161\u00ed\u0159en\u00e9, ale pochopen\u00ed jejich role je d\u016fle\u017eit\u00fdm krokem ke zlep\u0161en\u00ed tr\u00e1vic\u00edho zdrav\u00ed. <\/p>\n

Tato zji\u0161t\u011bn\u00ed otev\u00edraj\u00ed mo\u017enost personalizovan\u00fdch terapi\u00ed, kter\u00e9 obnovuj\u00ed hladiny mucinu<\/strong> a pom\u00e1haj\u00ed lidem zm\u00edrnit chronickou z\u00e1cpu, ani\u017e by se museli spol\u00e9hat na do\u010dasn\u00e1 \u0159e\u0161en\u00ed.<\/p>\n","protected":false},"excerpt":{"rendered":"

V\u00fdzkumn\u00edci identifikovali dva typy bakteri\u00ed, kter\u00e9 mohou hr\u00e1t kl\u00ed\u010dovou roli p\u0159i chronick\u00e9 z\u00e1cp\u011b, a potenci\u00e1ln\u011b tak otev\u00edraj\u00ed cestu k c\u00edlen\u011bj\u0161\u00ed l\u00e9\u010db\u011b. Studie publikovan\u00e1 v \u010dasopise Gut Microbes ukazuje, jak tyto bakterie naru\u0161uj\u00ed p\u0159irozenou lubrikaci tlust\u00e9ho st\u0159eva, co\u017e vede k pomal\u00e9mu tr\u00e1ven\u00ed. \u00daloha st\u0159evn\u00ed fl\u00f3ry p\u0159i defekaci Zdrav\u00e9 tr\u00e1ven\u00ed z\u00e1vis\u00ed na vyv\u00e1\u017een\u00e9 st\u0159evn\u00ed mikrobiot\u011b. Bakterie pom\u00e1haj\u00ed […]<\/p>\n","protected":false},"author":1,"featured_media":7421,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":""},"categories":[1],"tags":[],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/posts\/7422"}],"collection":[{"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/comments?post=7422"}],"version-history":[{"count":0,"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/posts\/7422\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/media\/7421"}],"wp:attachment":[{"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/media?parent=7422"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/categories?post=7422"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.schooler.org.ua\/cs\/wp-json\/wp\/v2\/tags?post=7422"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}